Alternative Transposition Generates New Chimeric Genes and Segmental Duplications at the Maize p1 Locus

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Alternative Transposition Generates New Chimeric Genes and Segmental Duplications at the Maize p1 Locus.

The maize Ac/Ds transposon family was the first transposable element system identified and characterized by Barbara McClintock. Ac/Ds transposons belong to the hAT family of class II DNA transposons. We and others have shown that Ac/Ds elements can undergo a process of alternative transposition in which the Ac/Ds transposase acts on the termini of two separate, nearby transposons. Because these...

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Mechanisms and impact of alternative transposition-induced segmental duplications

....................................................................................................... 89 Introduction ....................................................................................................... 90 Results ........................................................................................................ 92 Discussion ..............................................

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The maize Activator/Dissociation (Ac/Ds) elements are members of the hAT (hobo, Ac, and Tam3) superfamily of type II (DNA) transposons that transpose through a "cut-and-paste" mechanism. Previously, we reported that a pair of Ac ends in reversed orientation is capable of undergoing alternative transposition reactions that can generate large-scale chromosomal rearrangements, including deletions ...

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ژورنال

عنوان ژورنال: Genetics

سال: 2015

ISSN: 1943-2631

DOI: 10.1534/genetics.115.178210